Abnormalities in lymphocyte proliferation in classical and atypical measles infection

作者: Annette Finkel , Peter B. Dent

DOI: 10.1016/0008-8749(73)90004-X

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摘要: Abstract Impaired in vitro lymphocyte responses to PHA stimulation have been observed seven patients with acute classical measles infection, and three atypical measles. The impairment is evident only at suboptimal concentrations of disappears convalescence. Spontaneous DNA synthesis peripheral leukocytes was elevated both types patients, but the demonstrated a delayed return normal values as compared group. We failed demonstrate serum inhibitory factor an explanation for impaired lymphocytes these patients.

参考文章(16)
Gilbert Friday, Philip Fireman, Jesus Kumate, Effect of measles vaccine on immunologic responsiveness. Pediatrics. ,vol. 43, pp. 264- 272 ,(1969)
Joost J. Oppenheim, Evan M. Hersh, Brigid G. Leventhal, The Transformation of Column-Purified Lymphocytes with Nonspecific and Specific Antigenic Stimuli Journal of Immunology. ,vol. 101, pp. 262- 267 ,(1968)
Burton Zweiman, In Vitro Effects of Measles Virus on Proliferating Human Lymphocytes Journal of Immunology. ,vol. 106, pp. 1154- 1158 ,(1971)
Makoto Nihira, Thru Nakao, Jun-ichi Kadowaki, Reduction of Phytohemagglutinin.— Induced Lymphocyte Transformation in Patients with Measles Pediatrics. ,vol. 45, pp. 508- 508 ,(1970)
B. Zweiman, D. Pappagianis, H. Maibach, E.A. Hildreth, Effect of Measles Immunization on Tuberculin Hypersensitivity and in vitro Lymphocyte Reactivity International Archives of Allergy and Immunology. ,vol. 40, pp. 834- 841 ,(1971) , 10.1159/000230466
James I. Tennenbaum, Ronald L. St. Pierre, G James Cerilli, Evaluation of immunosuppressive therapy and clinical course in renal transplants by in vitro lymphocyte transformation. Transplantation. ,vol. 6, pp. 986- 990 ,(1968) , 10.1097/00007890-196812000-00004
G. M. Besser, Jane Davis, Catherine Duncan, Barbara Kirk, S. W. A. Kuper, Glandular fever and specific viral infections: uptake of tritiated thymidine by circulating leucocytes. British Journal of Haematology. ,vol. 13, pp. 189- 193 ,(1967) , 10.1111/J.1365-2141.1967.TB08730.X
D. Crowther, G. Hamilton Fairley, R.L. Sewell, Lymphoid cellular responses in the blood after immunization in man. Journal of Experimental Medicine. ,vol. 129, pp. 849- 869 ,(1969) , 10.1084/JEM.129.5.849