Non-Small Cell Lung Carcinoma: An Overview on Targeted Therapy.
作者： Ana Nascimento , Hassan Bousbaa , Domingos Ferreira , Bruno Sarmento
DOI: 10.2174/1389450115666140528151649
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摘要: … has developed ALN-VSP02, a lipid nanoparticle formulation encapsulating two modified siRNAs targeting either the VEGF or Eg5 kinesin. Eg5 is a member of the kinesin superfamily of …
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researchgate.net 参考文章(175)
Sung-Keum Seo, Hyeon-Ok Jin, Sang-Hyeok Woo, Young-Sun Kim, Sungkwan An, Jae-Ho Lee, Seok-Il Hong, Kee-Ho Lee, Tae-Boo Choe, In-Chul Park, Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. Journal of Thoracic Oncology. ,vol. 6, pp. 1313- 1319 ,(2011) , 10.1097/JTO.0B013E318220CAFF
Martin Reck, BIBF 1120 for the treatment of non-small cell lung cancer Expert Opinion on Investigational Drugs. ,vol. 19, pp. 789- 794 ,(2010) , 10.1517/13543784.2010.488220
Vasiliki Sarli, Athanassios Giannis, Targeting the Kinesin Spindle Protein: Basic Principles and Clinical Implications Clinical Cancer Research. ,vol. 14, pp. 7583- 7587 ,(2008) , 10.1158/1078-0432.CCR-08-0120
Lou Qian Zhang, Jun Wang, Feng Jiang, Lin Xu, Fu Yin Liu, Rong Yin, Prognostic Value of Survivin in Patients with Non-Small Cell Lung Carcinoma: A Systematic Review with Meta-Analysis PLoS ONE. ,vol. 7, pp. e34100- ,(2012) , 10.1371/JOURNAL.PONE.0034100
Esther Raskopf, Annabelle Vogt, Tilman Sauerbruch, Volker Schmitz, siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo. Journal of Hepatology. ,vol. 49, pp. 977- 984 ,(2008) , 10.1016/J.JHEP.2008.07.022
Patricia Galán-Malo, Laura Vela, Oscar Gonzalo, Rubén Calvo-Sanjuán, Lucía Gracia-Fleta, Javier Naval, Isabel Marzo, Cell fate after mitotic arrest in different tumor cells is determined by the balance between slippage and apoptotic threshold. Toxicology and Applied Pharmacology. ,vol. 258, pp. 384- 393 ,(2012) , 10.1016/J.TAAP.2011.11.021
David S. Hong, Maria E. Cabanillas, Jennifer Wheler, Aung Naing, Apostolia M. Tsimberidou, Lei Ye, Steven G. Waguespack, Mike Hernandez, Alder K. El Naggar, Savita Bidyasar, John Wright, Steven I. Sherman, Razelle Kurzrock, Inhibition of the Ras/Raf/MEK/ERK and RET Kinase Pathways with the Combination of the Multikinase Inhibitor Sorafenib and the Farnesyltransferase Inhibitor Tipifarnib in Medullary and Differentiated Thyroid Malignancies The Journal of Clinical Endocrinology and Metabolism. ,vol. 96, pp. 997- 1005 ,(2011) , 10.1210/JC.2010-1899
Vince D. Cataldo, Don L. Gibbons, Román Pérez-Soler, Alfonso Quintás-Cardama, Treatment of non-small-cell lung cancer with erlotinib or gefitinib. The New England Journal of Medicine. ,vol. 364, pp. 947- 955 ,(2011) , 10.1056/NEJMCT0807960
Roop Bora, RNA interference therapeutics for cancer: Challenges and opportunities (Review) Molecular Medicine Reports. ,vol. 6, pp. 9- 15 ,(2012) , 10.3892/MMR.2012.871
M Roshni Ray, David Jablons, Biao He, Lung cancer therapeutics that target signaling pathways: an update Expert Review of Respiratory Medicine. ,vol. 4, pp. 631- 645 ,(2010) , 10.1586/ERS.10.64