Carcinoma ex oncocytic Schneiderian (cylindrical cell) papilloma

摘要: Abstract Introduction: This study reviews the clinicopathologic features of carcinoma presenting in oncocytic Schneiderian papilloma (OSP; cylindrical cell papilloma), a rare histologically distinctive sharing with inverted papilloma. Materials and Methods: Nine cases ex OSP (1970–1990), six from files Armed Forces Institute Pathology (Washington, DC) three surgical pathology files, Presbyterian-University Hospital Eye Ear (Pittsburgh, PA), were studied. One case was previously reported. Clinical data obtained patients' medical records. All available histologic slides reviewed. Results: The patients (eight men, one woman) ranged age 48 to 83 years (mean age, 74 years). synchronous eight patients. In case, occurred 8 after diagnosed on biopsy. manifestations included nasal obstruction, “polyps,” epistaxis, proptosis. Radio-graphically, sinonasal mass present, often extension adjacent sites bone destruction. Most received postoperative irradiation. Of follow-up, four died two alive without disease at 1.5 7 years, respectively. types were: squamous (n = 6), high-grade mucoepidermoid 2), undifferentiated 1). Histologic transition observed between dysplastic/benign cases. Conclusion: Demonstration continuity dysplastic epithelium our nine indicates origin OSP, rather than coincidence neoplasms. Although benign, should be totally excised diagnosis because potential for malignant transformation.