Current and future trends in the oral pharmacotherapy of male erectile dysfunction.

摘要: The promising clinical data on the use of first orally active phosphodiesterase inhibitor sildenafil citrate (Viagra®) for treatment male erectile dysfunction have been accompanied by an increase in research activities physiology mechanism. This included both peripheral intracellular signal transduction corpus cavernosum as well central brain and spinal cord pathways that control penile erection. work provided basis development introduction several new therapeutic modalities into management is now offered to patients. Since concept ‘taking a pill’ cure illness or relief symptoms disease has become widely accepted consumers, pharmacological primarily focused selective, available drugs act via influencing regulatory mechanisms, combining high response rate advantage ‘on-dem...