Phosphodiesterase type 5 (PDE5) inhibitors for the treatment of erectile dysfunction.
作者： Philip Dorsey , Christopher Keel , Meghan Klavens , Wayne JG Hellstrom
DOI: 10.1517/14656561003698131
关键词:
摘要: Importance to the field: Since sildenafil was introduced 10 years ago, highly selective phosphodiesterase type 5 inhibitors (PDE5i) have changed medical management of erectile dysfunction (ED). A significant body research has been devoted use this class medication for treatment ED and advanced our understanding physiology. Recently, investigators noted potential benefits in various urologic non-urologic conditions, novel agents are late-stage trials.Areas covered review: Clinical basic science articles published between 1990 2009 were selected from multiple sources, including PubMed, Lexis-Nexis, EBSCO, manufacturer websites. Our search focused on clinical outcomes PDE5i other conditions publications examining pharmacologic effects.What reader will gain: This review provides a thorough description c...
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