Paradoxical inhibition of the effects of bradykinin by some sulfhydryl reagents.

作者: B. B. Vargaftig , Nguyen Dao Hai

DOI: 10.1007/BF01928265

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摘要: Plusieurs derives thiol et deux antioxidants inhibent la bronchoconstriction chez le cobaye, une partie de l'hypotension lapin liberation «rabbit aorta contracting substance» (RCS) dues a bradykinine Il est propose que les effets communs bradykinine, SRS-A, SRS-C l'acide arachidonique, qui sont bloques par des antiinflammatoires, acides, thiol, dus formation RCS, constituee peroxydes cicliques analogues aux precurseurs instables prostaglandines E 2 F alpha.

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