High contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed Multispectral Optoacoustic Tomography (tuMSOT)
作者： Andre C. Stiel , Xosé Luís Deán-Ben , Yuanyuan Jiang , Vasilis Ntziachristos , Daniel Razansky
DOI: 10.1364/OL.40.000367
关键词:
摘要: Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed increase the contrast-to-noise-ratios (CNRs) in imaging. In this way, two variants RSFP Dronpa with very similar spectra could be readily discriminated presence highly absorbing blood. Addition temporal unmixing multispectral tomography (tuMSOT) conjunction synthetic or genetically controlled photochromic contrast agents and customized photoswitching schedules can performance multiplexed high molecular
arxiv.org
128.84.21.199参考文章(21)
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