Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion

摘要: Observational studies have shown an inverse association between dietary calcium intake and body weight, a causal relation is likely. However, the underlying mechanisms are not understood. We examined whether high low intakes from mainly low-fat dairy products, in diets or normal protein content, effects on 24-h energy expenditure (EE) substrate oxidation, fecal fat excretion, concentrations of substrates hormones involved metabolism appetite. In all, 10 subjects participated randomized crossover study three isocaloric 1-week with: (LC/NP: 500 mg calcium, 15% (E%) protein), (HC/NP: 1800 15E% (HC/HP: 23E% protein). The had no effect EE but excretion increased ∼2.5-fold during HC/NP diet compared with LC/NP HC/HP (14.2 vs 6.0 5.9 g/day; P<0.05). also as (1045 684 668 kJ/day; There were blood cholesterol, free fatty acids, triacylglycerol, insulin, leptin, thyroid hormones. A short-term increase intake, together by ∼350 kJ/day. This observation may contribute to explain why high-calcium produces weight loss, it suggests that interaction level be important.