Gene-targeting studies of mammalian behavior : is it the mutation or the background genotype ?
作者： Robert Gerlai
DOI: 10.1016/S0166-2236(96)20020-7
关键词:
摘要: … For example, the ability to disrupt a single gene in a targeted manner might lead one to overlook the effects of other genes. Ignoring the genetic background might lead to …
elsevier.com
sci-hub.se 
researchgate.net 参考文章(25)
D. Goldowitz, R. E. Wimer, D. Wahlsten, Techniques for the Genetic Analysis of Brain and Behavior: Focus on the Mouse ,(1992)
Alexandra L. Joyner, Gene Targeting: A Practical Approach ,(2021)
G. R. Taylor, M. J. McPherson, B. D. Hames, PCR 2 : a practical approach IRL Press at Oxford University Press. ,(1995)
Marina R. Picciotto, Michele Zoli, Clement Léna, Alain Bessis, Yvan Lallemand, Nicolas LeNovère, Pierre Vincent, Emilio Merlo Pich, Philippe Brûlet, Jean-Pierre Changeux, Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain. Nature. ,vol. 374, pp. 65- 67 ,(1995) , 10.1038/374065A0
François Conquet, Zafar I. Bashir, Ceri H. Davies, Hervé Daniel, Francesco Ferraguti, Fabio Bordi, Karin Franz-Bacon, Angelo Reggiani, Valerie Matarese, Françoise Condé, Graham L. Collingridge, Francis Crépel, Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1 Nature. ,vol. 372, pp. 237- 243 ,(1994) , 10.1038/372237A0
Melina MacPhee, Kenneth P Chepenik, Rebecca A Liddell, Kelly K Nelson, Linda D Siracusa, Arthur M Buchberg, The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia Cell. ,vol. 81, pp. 957- 966 ,(1995) , 10.1016/0092-8674(95)90015-2
Richard G.M. Morris, Mary B. Kennedy, The Pierian Spring Current Biology. ,vol. 2, pp. 511- 514 ,(1992) , 10.1016/0960-9822(92)90001-Q
M Sibilia, E. Wagner, Strain-dependent epithelial defects in mice lacking the EGF receptor Science. ,vol. 269, pp. 234- 238 ,(1995) , 10.1126/SCIENCE.7618085
Steven Rose, The rise of neurogenetic determinism Nature. ,vol. 373, pp. 380- 382 ,(1995) , 10.1038/373380A0
A. Silva, R Paylor, J. Wehner, S Tonegawa, Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice Science. ,vol. 257, pp. 206- 211 ,(1992) , 10.1126/SCIENCE.1321493