The Psychotropic Effects of Vagus Nerve Stimulation in Epilepsy

作者: Eric J. Foltz , David M. Labiner

DOI: 10.1016/B978-0-12-374006-9.00019-9

关键词:

摘要: There is a better understanding of comorbid conditions associated with epilepsy, particularly psychiatric disorders that have led to new treatment strategies. Based on similar sites and mechanisms action, as well effects mood noted in the several antiepileptic medications subsequently been studied for use conditions. Carbamazapine, valproic acid, lamotrigine, among others, used bipolar disorder. These agents also adjunctive depression. Vagus nerve has briefly explained; it contains approximately 80% afferent fibers 20% efferent fibers. Sensory information from head, neck, thorax, abdomen carried nucleus solitary tract (NTS). From NTS, there are bilateral projections areas brain, including cerebellum, periaqueductal gray, raphe nucleus, locus coeruleus, limbic system, cerebral cortex. Thus, potential role regulating seizure activity, emotion, mood, pain.

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