Clinical utility of viscoelastic testing (TEG and ROTEM analyzers) in the management of old and new therapies for hemophilia.

摘要: Hemophilia A and B are rare inherited bleeding disorders resulting from deficiency of coagulation factors VIII IX respectively. In the past few decades, field hemophilia has witnessed pivotal management challenges therapeutic advances. Routine factor assays, while useful in classification severity treatment monitoring patients, have been shown to be limited use managing clinical presentations outcomes. This prompted investigation viscoelastic studies care, which established their utility various thrombotic states. this review, we will discuss critically assess current literature highlighting aspects including determination phenotype, patients with inhibitors, perioperative management, novel agents.