The Uni-Gold™ Streptococcus pneumoniae urinary antigen test: an interassay comparison with the BinaxNOW® Streptococcus pneumoniae test on consecutive urine samples and evaluation on patients with bacteremia.

摘要: The performance of the recently commercialized Uni-Gold™ Streptococcus pneumoniae test for detection pneumococcal antigen in urine was studied a multicenter study. First, we interassay agreement between and BinaxNOW® S. urinary on 337 consecutive samples sent to laboratory antigen. two tests performed similarly (κ = 0.82): both positive 27 cases, negative 299 with divergent results 11 cases. Secondly, were run from 203 patients bacteremia, including 51 bacteremia. sensitivities specificities 67 86 % Uni-Gold™, 57 % 94 % BinaxNOW®, respectively. false-positivity rate significantly higher compared Escherichia coli bacteremia (15 vs. 2.1 %, p = 0.04), tended be alpha-hemolytic streptococci (32 11 %, p = 0.13). When cases E. excluded analysis, overall 9/85 (11 %) 6/85 (7.1 %) BinaxNOW®. In conclusion, study showed that not inferior specificity suboptimal due false-positive However, patient populations usually subjected testing antigen, such as pneumonia meningitis patients, these pathogens is uncommon. diagnostic usefulness should further evaluated.