Comparison of Different Clinical Diagnostic Criteria for Depression in Alzheimer Disease

摘要: Objective Data in the literature show different estimates of prevalence depression patients with Alzheimer disease (AD) when classification systems are used. This study describes and clinical features AD based on five systems. Methods was a cross-sectional, observational 491 probable AD. Depression diagnosed using (International Classification Diseases, 10th Revision [ICD-10], Diagnostic Statistical Manual Mental Disorders, Fourth Edition [DSM–IV], Cambridge Examination for Disorder Elderly [CAMDEX], Provisional Criteria [PDC-dAD], Neuropsychiatric Inventory [NPI]). Results The 4.9% (95% confidence interval [CI]: 3.2–7.1) according to ICD-10 criteria; 9.8% CI: 7.3–12.6) CAMDEX; 13.4% 10.6–16.6) DSM–IV; 27.4% 23.6–31.5) PDC-dAD 43.7% 39.4–48.2) screening questions from NPI subscale. level agreement between low moderate (χ Conclusions shows that there is high variability rates depending diagnostic criteria used rate among analyzed. results suggest use generic such as ICD-10, CAMDEX, or DSM–IV provides compared specific PDC-dAD.