Novel circulating biomarkers for non-alcoholic fatty liver disease: A systematic review.
作者： Amirhossein Sahebkar , Elena Sancho , David Abelló , Jordi Camps , Jorge Joven
DOI: 10.1002/JCP.25779
关键词:
摘要: Currently, a liver biopsy remains the only reliable way to precisely diagnose non-alcoholic fatty disease (NAFLD) and establish severity of injury, presence fibrosis, architecture remodeling. However, cost intrinsic invasive procedure rules it out as gold standard diagnostic test, imaging test are not best choice due price, currently is being refined. The lack biomarker NAFLD pushes develop this new line research. aim present systematic review clarify update all biomarkers described in literature until recently. We highlight α-ketoglutarate CK18-F potential NAFLD. methodological differences, we propose implementation international, multicenter, multiethnic studies with larger population size, proven diagnosis analyze compare silent evolution
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