Oestrogen exposure and breast cancer risk
作者： Ruth C Travis , Timothy J Key
DOI: 10.1186/BCR628
关键词:
摘要: Epidemiological and experimental evidence implicates oestrogens in the aetiology of breast cancer. Most established risk factors for cancer humans probably act through hormone-related pathways, increased concentrations circulating have been found to be strongly associated with postmenopausal women. This article explores hypothesis that oestrogen exposure is a major determinant We review recent data on risk, consider oestrogen-related examine possible mechanisms might account effects oestrogen. Finally, we discuss how these advances influence strategies reducing incidence
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