Antralization of the gastric mucosa of the incisura angularis and its gastrin expression.
作者： Pernilla Lagergren , Edgar Jaramillo , Gabriella Nesi , Carlos A Rubio , Gaku Suzuki
DOI:
关键词:
摘要: The frequency of antrum-type mucosa and gastrin expression in gastric biopsies from the incisura angularis was assessed 60 consecutive patients having gastrointestinal symptoms. Following recommendations updated Sydney System for classification grading gastritis, two were taken antrum, one corpus. Sections stained with H&E, Giemsa gastrin. Gastrin-positive cells semi-quantified as: 0 (none), /=50 gastrin-labelled cells/40x field. Antrum-type at (called antralization) occurred 30% without inflammation, but 69% those H. pylori-induced 64% autoimmune gastritis. At incisura, (>/=10) found 62% (18/29) showing antralization, only 20% (3/15) transitional-type (p<0.05) none 16 fundic-type mucosa. similarity between antrum antral-type substantiates notion that antralization is a metaplastic transformation. significantly higher gastritis than strongly suggests chronic inflammation per se triggers irrespective presence or absence pylori infection.
researchgate.net 参考文章(25)
Nihal Kilinç, Fikri Canoruç, Serif Yilmaz, Mehmet Dursun, Vahit Yükselen, Alpaslan Tuzcu, Evaluation of optimal gastric mucosal biopsy site and number for identification of Helicobacter pylori, gastric atrophy and intestinal metaplasia. Hepato-gastroenterology. ,vol. 51, pp. 1732- 1735 ,(2004)
Shigeo Takaishi, Guanglin Cui, Dana M. Frederick, Jane E. Carlson, JeanMarie Houghton, Andrea Varro, Graham J. Dockray, Zhongming Ge, Mark T. Whary, Arlin B. Rogers, James G. Fox, Timothy C. Wang, Synergistic Inhibitory Effects of Gastrin and Histamine Receptor Antagonists on Helicobacter-Induced Gastric Cancer Gastroenterology. ,vol. 128, pp. 1965- 1983 ,(2005) , 10.1053/J.GASTRO.2005.03.027
Yoram Elitsur, Zandra Lawrence, William E. Triest, Distribution of Helicobacter pylori organisms in the stomachs of children with H. pylori infection Human Pathology. ,vol. 33, pp. 1133- 1135 ,(2002) , 10.1053/HUPA.2002.129201
Robert M. Genta, David Y. Graham, Comparison of biopsy sites for the histopathologic diagnosis of Helicobacter pylori: a topographic study of H. pylori density and distribution. Gastrointestinal Endoscopy. ,vol. 40, pp. 342- 345 ,(1994) , 10.1016/S0016-5107(94)70067-2
André Blum, Manfred Stolte, Heiko Müller, Nicholas J. Talley, Colm O’Morain, Elisabeth Bolling-Sternevald, Marie Sundin, Sven Eriksson, In patients with Helicobacter pylori gastritis and functional dyspepsia, a biopsy from the incisura angularis provides useful diagnostic information. Pathology Research and Practice. ,vol. 202, pp. 405- 413 ,(2006) , 10.1016/J.PRP.2006.01.011
Harry Hua-Xiang Xia, Jamshid S. Kalantar, Nicholas J. Talley, Jenny Ma Wyatt, Stuart Adams, Karen Cheung, Hazel M. Mitchell, Antral-type mucosa in the gastric incisura, body, and fundus (antralization): a link between Helicobacter pylori infection and intestinal metaplasia? The American Journal of Gastroenterology. ,vol. 95, pp. 114- 121 ,(2000) , 10.1111/J.1572-0241.2000.01609.X
HARRY HUA-XIANG XIA, BENJAMIN CHUN-YU WONG, GUI-SHUI ZHANG, YI YANG, JENNY MA WYATT, STUART ADAMS, KAREN CHEUNG, SHIU KUM LAM, NICHOLAS J TALLEY, Antralization of gastric incisura is topographically associated with increased gastric epithelial apoptosis and proliferation, but not with CagA seropositivity. Journal of Gastroenterology and Hepatology. ,vol. 19, pp. 1257- 1263 ,(2004) , 10.1111/J.1440-1746.2004.03489.X
Barik A. Salih, M. Fatih Abasiyanik, Huseyin Saribasak, Osman Huten, Ersan Sander, A follow-up study on the effect of Helicobacter pylori eradication on the severity of gastric histology. Digestive Diseases and Sciences. ,vol. 50, pp. 1517- 1522 ,(2005) , 10.1007/S10620-005-2871-7
Terezinha Marques, Leonor David, Celso Reis, Ana Nogueira, Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseases. Pathology Research and Practice. ,vol. 201, pp. 665- 672 ,(2005) , 10.1016/J.PRP.2005.03.007
Yi Yang, Harry H.-X. Xia, Nicholas J. Talley, Gui-Shui Zhang, Jenny Ma Wyatt, Stuart Adams, Karen Cheung, Shiu Kum Lam, Benjamin C.Y. Wong, Antralization of gastric incisura is topographically associated with increased gastric epithelial apoptosis and proliferation, but not with CagA seropositivity Gastroenterology. ,vol. 124, ,(2003) , 10.1016/S0016-5085(03)82345-4