Functional adaptation of tRNA population

作者: Jean-Pierre Garel

DOI: 10.1016/S0022-5193(74)80054-8

关键词:

摘要: Optimum efficiency of protein biosynthesis is obtained through continuous, selective adjustment cytoplasmic tRNA population to the amino acid composition proteins being synthetized. We call this “functional or quantitative adaptation”. This regulation phenomenon has been found in highly differentiated cell systems such as silkgland Bombyx mori L., reticulocytes, plasmocytoma and lens. It can be applied other Escherichia coli , yeast liver. Implications functional adaptation are discussed terms a modulated with each species regulated independently.

参考文章(22)
B.P. Doctor, John A. Mudd, SPECIES SPECIFICITY OF AMINO ACID ACCEPTOR RIBONUCLEIC ACID AND AMINOACYL SOLUBLE RIBONUCLEIC ACID SYNTHETASES. Journal of Biological Chemistry. ,vol. 238, pp. 3677- 3681 ,(1963) , 10.1016/S0021-9258(19)75325-3
J Ilan, Amino Acid Incorporation and Aminoacyl Transfer in an Insect Pupal System Journal of Biological Chemistry. ,vol. 243, pp. 5859- 5866 ,(1968) , 10.1016/S0021-9258(18)94500-X
Giulio L. Cantoni, David R. Davies, Procedures in nucleic acid research Harper & Row , University of Tokyo Press. ,(1966)
Michael Litt, David Kabat, Studies of Transfer Ribonucleic Acids and of Hemoglobin Synthesis in Sheep Reticulocytes Journal of Biological Chemistry. ,vol. 247, pp. 6659- 6664 ,(1972) , 10.1016/S0021-9258(19)44742-X
Gérard Chavancy, Jacques Daillie, Jean-Pierre Garel, Adaptation fonctionnelle des t-RNA à la biosynthèse protéique dans un système cellulaire hautement différencié Biochimie. ,vol. 53, pp. 1187- 1194 ,(1971) , 10.1016/S0300-9084(71)80183-9
D W E Smith, The measurement of transfer ribonucleic acid synthesis during induction of the lactose operon. Journal of Biological Chemistry. ,vol. 243, pp. 3361- 3366 ,(1968) , 10.1016/S0021-9258(18)93316-8
Wen-Kuang Yang, Isoaccepting transfer RNA's in mammalian differentiated cells and tumor tissues. Cancer Research. ,vol. 31, pp. 639- 643 ,(1971)