Hantaviruses and a neglected environmental determinant.

摘要: Most human pathogenic hantaviruses cause severe hemorrhagic fevers with a high rate of fatalities, such as occurs due to the genotypes causing hantavirus cardiopulmonary syndrome carried by New World Sigmodontinae and Neotominae rodents. An increasing number outbreaks possibility cases spreading over international borders have led greater interest in these viruses environmental determinants that facilitate their transmission. Rodents, shrews, moles bats act reservoir hosts hantaviruses, within transmission flow, prevalence distribution infection is influenced range factors. Climate change landscape alteration affect transmission, but outcomes can differ among different for same virus differentbiomes. However, it evident underlying mechanisms mediate are largely unknown, so much work remains be done regarding dynamics hantaviruses. Overall, our review highlights importance examining interactions several trophic levels (density trait-mediated indirect effects) linking predation risk develop an ecological framework understand disease natural, preserved degraded systems.