Chemotherapeutic induction of egr-1 promoter activity
作者： Ralph R. Weichselbaum , Helena Mauceri , Mitchell Posner , James Park , Donald W. Kufe
DOI:
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摘要: The present invention provides for improved therapeutic regimens treating benign hyperproliferative diseases and cancers. Egr-1 promoter, long known to be radiation-responsive, has now been shown inducible DNA damaging chemical agents, many of which themselves are used in therapies. Thus, the advantages combination a an expression vector containing gene driven by promoter.
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