Indicators of Need for Mechanical Ventilation in Duchenne Muscular Dystrophy and Spinal Muscular Atrophy

摘要: Study objectives The purpose was to investigate a possible relationship between different parameters of physical function, spirometric measurements, and the approaching need for mechanical ventilation. Design A nonrandomized, prospective, descriptive study 11 patients with spinal muscular atrophy type II (SMA-II) 14 Duchenne dystrophy (DMD). At home visit, anthropometric indices age, height, weight were recorded, degree disability scored, measurement strength eight muscle groups spirometry performed. interdependence variables analyzed intergroup differences evaluated. Eighteen months later, it found that one authors (B.J.), who blind results first examination had instituted ventilation on seven patients. data retrospectively their predictive value as indicators ventilator dependency. Results needed DMD highest score (Egen Klassifikation [EK] sum >20) smallest values FVC Conclusion In this investigation, combination EK FVC% provided better indication in than separately.