Birth weight and other perinatal characteristics and childhood leukemia in California
作者： S. Oksuzyan , C.M. Crespi , M. Cockburn , G. Mezei , L. Kheifets
DOI: 10.1016/J.CANEP.2012.08.002
关键词:
摘要: Abstract Aims. We conducted a large registry-based study in California to investigate the association of perinatal factors and childhood leukemia with analysis two major subtypes, acute lymphocytic (ALL) myeloid (AML). Methods. linked cancer birth registries obtain information on 5788 cases controls matched age sex (1:1). examined weight, gestational age, pregnancy order, parental ages, specific conditions during risk total leukemia, ALL AML using conditional logistic regression, adjustment for potential confounders. Results. The odds ratio (OR) per 1000g increase weight was 1.11 both ALL. OR were highest babies weighing ≥4500g reference Conclusions. Our results suggest that high LGA associated increased SGA decreased ALL, being first-born AML, advanced paternal These findings associations depend highly subtype leukemia.
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