Effects of flaxseed and Hypericum perforatum on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women: a systematic review and meta-analysis.
作者： Masumeh Ghazanfarpour , Robab Latifnejad Roudsari , Ramin Sadeghi , Maliheh Afiat , Talat Khadivzadeh
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摘要: In this study, we aimed at evaluation of the efficacy Hypericum perforatum and flaxseed on hot flash, vaginal atrophy estrogen-dependent cancers in menopausal women Materials Methods: We searched MEDLINE, Scopus, Cochrane Central Register Controlled Trials (RCT) to explore trials that assessed effectiveness H. cancers. regard, following terms were used "menopause AND OR Linum usitatissimum. Only randomized controlled included study. Results: Nine RCTs systematic review. Based literature, showed beneficial effect flash frequency intensity, which was not statistically significant. According two trials, estrogenic effects; however, no conclusion regarding cancer promoting or protecting effects can be made. The evidence alleviating also limited due inconsistent findings regard. One trial declared Vitex agnus-castus comparable decrease flashes. Conclusion: results our review suggest vasomotor symptom with both perforatum. Consistent estrogen- dependent maturation value is small number related flaxseed. Further are still needed confirm
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