Telmisartan ameliorates adipoR1 and adipoR2 expression via PPAR-γ activation in the coronary artery and VSMCs.
作者： Xuhua Shen , Hongwei Li , Weiping Li , Xing Wu , Zhijun Sun
DOI: 10.1016/J.BIOPHA.2017.08.041
关键词:
摘要: … 4A and B, AdipoR1 and AdipoR2 mRNA and protein level in coronary VSMCs were … AdipoR1 and AdipoR2 in coronary VSMCs. Pretreatment of GW9662, however, significantly …
sci-hub.se 参考文章(39)
Chengyu Jiang, Adrian T. Ting, Brian Seed, PPAR-γ agonists inhibit production of monocyte inflammatory cytokines Nature. ,vol. 391, pp. 82- 86 ,(1998) , 10.1038/34184
N. Suksomboon, N. Poolsup, T. Prasit, Systematic review of the effect of telmisartan on insulin sensitivity in hypertensive patients with insulin resistance or diabetes Journal of Clinical Pharmacy and Therapeutics. ,vol. 37, pp. 319- 327 ,(2012) , 10.1111/J.1365-2710.2011.01295.X
Hongbo He, Dachun Yang, Liqun Ma, Zhidan Luo, Shuangtao Ma, Xiaoli Feng, Tingbing Cao, Zhencheng Yan, Daoyan Liu, Martin Tepel, Zhiming Zhu, Telmisartan prevents weight gain and obesity through activation of peroxisome proliferator-activated receptor-δ-dependent pathways. Hypertension. ,vol. 55, pp. 869- 879 ,(2010) , 10.1161/HYPERTENSIONAHA.109.143958
Chiara Caselli, Role of adiponectin system in insulin resistance Molecular Genetics and Metabolism. ,vol. 113, pp. 155- 160 ,(2014) , 10.1016/J.YMGME.2014.09.003
G Chinetti, C Zawadski, J.C Fruchart, B Staels, Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARα, PPARγ, and LXR Biochemical and Biophysical Research Communications. ,vol. 314, pp. 151- 158 ,(2004) , 10.1016/J.BBRC.2003.12.058
F. Halperin, J. A. Beckman, M. E. Patti, M. E. Trujillo, M. Garvin, M. A. Creager, P. E. Scherer, A. B. Goldfine, The role of total and high-molecular-weight complex of adiponectin in vascular function in offspring whose parents both had type 2 diabetes. Diabetologia. ,vol. 48, pp. 2147- 2154 ,(2005) , 10.1007/S00125-005-1901-5
S. Honjo, Y. Nichi, Y. Wada, Y. Hamamoto, H. Koshiyama, Possible beneficial effect of telmisartan on glycemic control in diabetic subjects. Diabetes Care. ,vol. 28, pp. 498- 498 ,(2005) , 10.2337/DIACARE.28.2.498
P. E. Scherer, Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes. ,vol. 55, pp. 1537- 1545 ,(2006) , 10.2337/DB06-0263
Enrique Z Fisman, Alexander Tenenbaum, Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease? Cardiovascular Diabetology. ,vol. 13, pp. 103- 103 ,(2014) , 10.1186/1475-2840-13-103
Toshimasa Yamauchi, Kazuo Hara, Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Philippe Froguel, Ryozo Nagai, Takashi Kadowaki, Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine. Current Drug Targets - Immune, Endocrine & Metabolic Disorders. ,vol. 3, pp. 243- 253 ,(2003) , 10.2174/1568008033340090