Temporal bone studies of the human peripheral vestibular system. Meniere's disease.

摘要: Quantitative assessments of vestibular hair cells and Scarpa's ganglion were performed on temporal bones from 24 patients with well-documented Meniere's disease. Of these, 18 had unilateral disease 6 bilateral Vestibular cell counts made in each the 5 sense organs by Nomarski (differential interference contrast) microscopy. Hair expressed as densities: number per 0.01 mm2 surface area sensory epithelium. The results compared age- sex-matched normal data. type I densities for all within range normative On other hand, there was a significant loss (p < .01) II 3 cristae both maculae. There also .001) when findings indicate selective These new observations have implications regarding pathophysiological mechanism clinical manifestations