Nanoparticle brain delivery: a guide to verification methods.
作者： Robert A Yokel
关键词:
摘要: Many reports conclude nanoparticle (NP) brain entry based on bulk analysis. Bulk includes blood, cerebrospinal fluid and blood vessels within the contributing to blood-brain blood-cerebrospinal barriers. Considering as neurons, glia their extracellular space (brain parenchyma), most studies did not show parenchymal NP entry. Blood-brain barriers anatomy function are reviewed. Methods demonstrating presented. Results versus classified. Studies reviewed, critiqued classified illustrate results Brain, peripheral organ timecourses compared related evidence suggesting timecourse informs about
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