Cationic contrast agents and methods of use thereof

摘要: The present invention provides compounds useful as contrast agents, such for the CT imaging of cartilage tissue. agents are generally iodinated organic molecules that positively charged under physiological environments. Also provided compositions containing and methods using including, example, monitoring glycosaminoglycan content in non-invasive analytical techniques diagnosis osteoarthritis its earliest stages. also improvements over existing monitoring, which tend to exhibit low residence times require high dosages.