Iodinated x-ray contrast media

作者: Håkan Wikström , Ib Leunbach , Arne Berg , Harald Dugstad , Klaes Golman

DOI:

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摘要: The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula (I) (wherein each C6R5 moiety may be the same or different; R denotes a hydrogen iodine atom group M, two three non-adjacent groups on denoting atoms and one, M groups; X providing 1, 2 3 chain linking groups, preferably where is contains in bridging carbonyloxy being triodophenyl which other than hydrogen; independently non-ionic hydrophilic moiety, comprising monohydroxy- polyhydroxy-alkyl group) isomers, especially stereoisomers rotamers, thereof.

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