Epithelial tissue targeting agent
作者： Mich B. Hein , Andrew C. Hiatt , John H. Fitchen
DOI:
关键词:
摘要: Targeting molecules for use in delivering biological agents to epithelial tissue are disclosed. Upon delivery, the agent(s) may remain within an cell or undergo transepithelial transport via transcytosis. The targeting be used, example, delivery of therapeutic agents.
lens.org 参考文章(50)
Wei-Chiang Shen, Jiansheng Wan, Compositions and methods for enhanced transepithelial and transendothelial transport or active agents ,(1991)
M E Lamm, J K Robinson, C S Kaetzel, Epithelial transcytosis of monomeric IgA and IgG cross-linked through antigen to polymeric IgA. A role for monomeric antibodies in the mucosal immune system. Journal of Immunology. ,vol. 152, pp. 72- 76 ,(1994)
Per Brandtzaeg, Kåre Baklien, Intestinal secretion of IgA and IgM: a hypothetical model. Ciba Foundation symposium. pp. 77- 113 ,(1977) , 10.1002/9780470720288.CH5
ABDALLA Rifai, MART Mannik, None, Clearance kinetics and fate of mouse IgA immune complexes prepared with monomeric or dimeric IgA. Journal of Immunology. ,vol. 130, pp. 1826- 1832 ,(1983)
A J Husband, A W Cripps, R F Sheldrake, D L Watson, Selective transport of serum-derived IgA into mucosal secretions. Journal of Immunology. ,vol. 132, pp. 363- 368 ,(1984)
Hiroshi Nagura, Paul K. Nakane, William R. Brown, Translocation of Dimeric IgA through Neoplastic Colon Cells in Vitro Journal of Immunology. ,vol. 123, pp. 2359- 2368 ,(1979)
Kenneth R. Youngman, Claudio Fiocchi, Charlotte S. Kaetzel, Charlotte S. Kaetzel, Inhibition of IFN-gamma activity in supernatants from stimulated human intestinal mononuclear cells prevents up-regulation of the polymeric Ig receptor in an intestinal epithelial cell line. Journal of Immunology. ,vol. 153, pp. 675- 681 ,(1994)
Leon N. Carayannopoulos, Edward E. Max, Jonathan M. Hexham, J. Donald Capra, RECOMBINANT HUMAN IgA-J. CHAIN DIMER ,(1998)
Inder M Verma, Nikunj Somia, None, Gene therapy -- promises, problems and prospects Nature. ,vol. 389, pp. 239- 242 ,(1997) , 10.1038/38410