Novel epithelial tissue imaging agent
作者： Mich B. Hein , Andrew C. Hiatt , John H. Fitchen
DOI:
关键词:
摘要: Targeting molecules are provided for use in delivering imaging agents to epithelial tissue. The targeting molecule comprises a polypeptide that forms closed covalent loop, contains at least three peptide domains having β-sheet character, each of the being separated by lacking character. specifically binds basolateral factor attached domain an cell surface causing internalization linked agent into cells. or may be amino acid sequence directs delivery carcinoma cell, nucleus, endoplasmic reticulum.
lens.org参考文章(19)
Mich B. Hein, Andrew C. Hiatt, John H. Fitchen, Epithelial tissue targeting agent ,(1998)
Wei-Chiang Shen, Jiansheng Wan, Compositions and methods for enhanced transepithelial and transendothelial transport or active agents ,(1991)
Srinivasan Rajaraman, Randall M. Goldblum, Assay for free secretory component and methods for monitoring organ rejection United States Patent and Trademark Office. ,(1992) , 10.26153/TSW/1790
Leon N. Carayannopoulos, Edward E. Max, Jonathan M. Hexham, J. Donald Capra, RECOMBINANT HUMAN IgA-J. CHAIN DIMER ,(1998)
Sharon S. Carpenter-Green, Michael W. Fountain, Alan L. Weiner, Robert P. Lenk, Localized delivery using fibronectin conjugates ,(1993)
Mich B. Hein, Andrew C. Hiatt, John H. Fitchen, Epithelial cell targeting agent ,(1998)
Andrew Stuart Janoff, Mircea Constantine Popescu, Carl R. Alving, Drug preparations of reduced toxicity. ,(1984)
Jeffrey Schlom, David Colcher, Second generation monoclonal antibodies having binding specificity to tag-72 and human carcinomas and methods for employing the same ,(1988)
Hubert J. P. Schoemaker, Barbara L. Westrick, Jack R. Wands, Vincent R. Zurawski, Immunoassay for multi-determinant antigens using high-affinity ,(1984)