Organ-wide and ploidy-dependent regulation both contribute to cell-size determination: evidence from a computational model of tomato fruit.

摘要: The development of a new organ is the result coordinated events cell division and expansion, in strong interaction with each other. This study presents dynamic model tomato fruit that includes division, endoreduplication, expansion processes. used to investigate potential interactions among these developmental processes within context neo-cellular theory. In particular, different control schemes (either cell-autonomous or organ-controlled) are tested compared experimental data from two contrasting genotypes. shows pure fails reproduce observed cell-size distribution, an organ-wide required order get realistic variations. also supports role endoreduplication as important determinant final size suggests direct effect on needed obtain significant correlation between ploidy, real data.