Biochemical sudies on a low molecular weight antiplasmin of human blood
作者： Paul T.K. Mui , Pankaj Ganguly
DOI: 10.1016/0003-9861(77)90100-X
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摘要: Abstract We previously reported a low molecular weight antiplasmin present in human platelets and plasma. This material as isolated by ultrafiltration was heterogeneous. The fraction showing maximum inhibition has been further purified countercurrent distribution. N-terminal residue of this inhibitor is alanine. Amino acid analysis showed glycine to be the predominant residue, no basic amino detected. Kinetic studies suggested competitive plasmin via enzyme-inhibitor complex formation. Carbohydrate phosphate could not These data were similar for both platelet serum antiplasmin. relationship between remains unclear. may contribute consolidation thrombus.
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