作者: V S Gordeev , W P Maksymowych , S M A A Evers , A Ament , L Schachna
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摘要: Objectives: In the bio-psycho-social model of health, role contextual factors, either environmental or personal is recognized. The objective this study was to assess impact a number factors on self-reported disease specific and generic health-related quality life in patients with ankylosing spondylitis (AS). Methods: 522 AS from Canada Australia completed postal questionnaire including socio-demographic variables, activity (BASDAI), function (BASFI), (ASQoL EQ-5D) helplessness (RAI/helplessness). contribution (nationality, ethnicity, marital status, education, employment helplessness) addition functioning disability (BASDAI BASFI) analyzed using multivariate regression analyses. Interactions between variables were explored. Results: Contextual explained 37 47% variance EQ-5D ASQoL, respectively. Helplessness most important factors. Their independent strong effect (BASDAI) functional limitations (BASFI). When ASQoL outcome, an interaction seen education when education. Conclusions: Of explored study, had life. lower not being employed stronger. especially employment, should receive more attention interpreting data