Retrograde autologous priming of the cardiopulmonary bypass circuit reduces blood transfusion after coronary artery surgery

作者: Subramaniam Balachandran , Michael H. Cross , Sivagnanam Karthikeyan , Anilkumar Mulpur , Stephen D. Hansbro

DOI: 10.1016/S0003-4975(02)03513-0

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摘要: Abstract Background . Hemodilution occurring with cardiopulmonary bypass imposes a risk for blood transfusion. Autologous priming of the circuit at initiation partially replaces solution autologous blood. We examined efficacy in reducing Methods One hundred and four patients were entered into prospective, randomized, controlled study. Initiation was or without priming. Results With priming, mean volume 808.8 ± 159.3 mL replaced This allowed higher hematocrit value on admission to intensive care unit discharge from hospital. In all, 49% control group required transfusion compared 17% ( p = 0.0007). The transfused 277.6 363.8 70.1 173.5 0.0005). Conclusions. Retrograde reduces homologous owing reduction volume.

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