Immunoreactive-β-endorphin, -adrenocorticotropin and -calcitonin in extracts of anaplastic or differentiated (rat) medullary thyroid carcinoma

作者: Tamotsu Shibasaki , Leonard Deftos , Roger Guillemin

DOI: 10.1016/0006-291X(79)91173-2

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摘要: Summary Substances with β-endorphin-like and adrenocorticotropin-like immunoreactivity were observed in extracts of both differentiated anaplastic rat medullary thyroid carcinoma. In the tumor extracts, molar ratios immunoreactive β-endorphin to immunoreactive-adrenocorticotropin statistically equal 1.0 while no consistent relationship was concentrations these two substances that immunoreactive-calcitonin.

参考文章(13)
Ronald William Raven, Modern trends in oncology Butterworths. ,(1973)
F Sundler, O Ljungberg, L Björklund, J Alumets, R Håkanson, Somatostatin-immunoreactive cells in medullary carcinoma of the thyroid. American Journal of Pathology. ,vol. 88, pp. 381- 386 ,(1977)
Roger Guillemin, Nicholas Ling, Therese Vargo, Radioimmunoassays for α-endorphin and β-endorphin Biochemical and Biophysical Research Communications. ,vol. 77, pp. 361- 366 ,(1977) , 10.1016/S0006-291X(77)80205-2
N Ishikawa, S Hamada, Association of medullary carcinoma of the thyroid with carcinoembryonic antigen British Journal of Cancer. ,vol. 34, pp. 111- 115 ,(1976) , 10.1038/BJC.1976.133
Ilona Szijj, Zsolt Csapó, Ferenc A. László, Kálmán Kovács, Medullary cancer of the thyroid gland associated with hypercorticism Cancer. ,vol. 24, pp. 167- 173 ,(1969) , 10.1002/1097-0142(196907)24:1<167::AID-CNCR2820240121>3.0.CO;2-S
C.J.M. Lips, J. Van Der Sluys Veer, J.A. Van Der Donk, R.H. Van Dam, W.H.L. Hackeng, COMMON PRECURSOR MOLECULE AS ORIGIN FOR THE ECTOPIC-HORMONE-PRODUCING-TUMOUR SYNDROME The Lancet. ,vol. 311, pp. 16- 18 ,(1978) , 10.1016/S0140-6736(78)90361-6
JACQUELINE G. PARTHEMORE, LEONARD J. DEFTOS, Calcitonin Secretion in Normal Human Subjects* The Journal of Clinical Endocrinology & Metabolism. ,vol. 47, pp. 184- 188 ,(1978) , 10.1210/JCEM-47-1-184
Leonard J. Deftos, Douglas Burton, Henry G. Bone, Bayard D. Catherwood, Jacqueline G. Parthemore, Robert Y. Moore, Scott Minick, Roger Guillemin, Immunoreactive calcitonin in the intermediate lobe of the pituitary gland. Life Sciences. ,vol. 23, pp. 743- 748 ,(1978) , 10.1016/0024-3205(78)90075-9
Shigetada Nakanishi, Akira Inoue, Toru Kita, Akira Inoue, Masahiro Nakamura, Annie C. Y. Chang, Stanley N. Cohen, Shosaku Numa, Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor. Nature. ,vol. 278, pp. 423- 427 ,(1979) , 10.1038/278423A0