Impact of cardiovascular risk factors on vessel wall inflammation and calcified plaque burden differs across vascular beds: a PET-CT study

摘要: To evaluate the effect of age, gender and cardiovascular risk factors on vessel wall inflammation calcified plaque burden in different vascular beds as assessed by PET/CT. 315 patients (mean age: 57.8 years, 123 male 192 female) who underwent whole body 18F-FDG PET/CT examinations were included study. Blood pool-corrected standardised uptake value (TBR) score (CPS, grade 0–4) determined thoracic abdominal aorta, both common carotid iliac arteries. The following documented: Age ≥65 years (n = 114), 123), diabetes 15), hyperlipidemia 62), hypertension 76), mass index (BMI) ≥ 30 38), current smoker 32). Effects TBR CPS arterial using multivariate regression analysis. In aorta was independently associated with age gender, diabetes. smoking. Independent associations arteries found for BMI CPS. arteries, ≥65, hypertension, Findings this study demonstrate that impact differs across territories. Overall, more closely compared to TBR.