Stability analysis of delay differential equation models of HIV-1 therapy for fighting a virus with another virus
作者： Cuifang Lv , Zhaohui Yuan
DOI: 10.1016/J.JMAA.2008.11.026
关键词:
摘要: Considering two kinds of delays accounting, respectively, for (i) a latent period between the time target cells are contacted by virus particles and virions enter (ii) production new to be produced within released from infected cells, we develop analyze mathematical model HIV-1 therapy fighting with another virus. For different values basic reproduction number second number, investigate stability infection-free equilibrium, single-infection equilibrium double-infection equilibrium. We conclude that increasing will decrease number. Our results have potential applications in therapy. The approach use here is combination analysis characteristic equations, Fluctuation Lemma Lyapunov function.
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