Rationale and design of a study using a standardized locally procured macronutrient supplement as adjunctive therapy to HIV treatment in Kenya
作者： Kevin A. Sztam , Murugi Ndirangu , Muhsin Sheriff , Stephen M. Arpadi , Mark Hawken
DOI: 10.1080/09540121.2012.752564
关键词:
摘要: Poor nutritional status at initiation of antiretroviral therapy (ART) is predictive mortality. Decreased dietary intake a major determinant weight loss in HIV. Despite biological rationale to treat undernutrition adults receiving ART, few studies have provided data on feasibility, safety, effectiveness, and sustainability specific macronutrient supplements with HIV treatment adults, especially such as food basket, supplement approach seldom evaluated spite its wide use. We present the design for study locally procured given HIV-infected patients initiating ART body mass index (BMI) ≤20.0 kg/m2. The objective was determine feasibility procurement, distribution, safety obtain preliminary effectiveness supplement. comparative 200 adult participants two Kenya government-supported clinics. primary outcome BMI 24 weeks. Supplement dur...
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