Hypervascular hepatocellular carcinoma in the cirrhotic liver: diffusion-weighted imaging versus superparamagnetic iron oxide-enhanced MRI

摘要: Abstract Purpose The purpose of the study was to validate diffusion-weighted imaging (DWI) in assessment hypervascular hepatocellular carcinoma (HCC) compared with superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MRI) cirrhotic liver. Material and Methods Forty-six consecutive patients 106 focal lesions liver who underwent DWI using three b factors gadopentetate dimeglumine-enhanced dynamic MRI followed by SPIO-enhanced were enrolled. Two independent radiologists evaluated two separated image sets (SPIO set, T2*-weighted images; MRI) assigned confidence levels for diagnosis HCC a five-point scale each lesion. Area under receiver operating characteristic curve ( A z ) calculated set. Results value set larger than SPIO both readers (reader 1, 0.936 vs. 0.900, P =.050; reader 2, 0.938 0.905, =.110). For sensitivity 93.1% 86.2%, =.146; 95.4% 88.5%, =.070) specificity 89.5% 73.7%, =.250; 79.0% =1.000) diagnosis, superior without statistically significant differences. Conclusion HCC, combination provides comparable or slightly better information MRI.