Adherence to guidelines of antibiotic prophylactic use in surgery: a prospective cohort study in North West Bank, Palestine

摘要: Surgical site infection is a major contributor to increased mortality and health care costs globally which can be reduced by appropriate antibiotic prophylactic use. In Palestine, there no published data about preoperative This study aims find the pattern of antimicrobial prophylaxis use evaluating time first dose, selection duration after surgery in three governmental hospitals North West Bank/ Palestine during 2011. After approval Institutional Review Board, prospective cohort included total 400 abdominal, orthopedic, gynecological operations were performed period. Trained clinical pharmacists observed selected 301 followed patient’s files for intended parameters. Compliance administration was evaluated according guidelines American Society Hospital Pharmacist. Data analyzed using SPSS version 16 applying descriptive methods. Relationship between guideline compliance operation factors such as type surgery, patient unit, hospital shift, addition provider’s age, gender, experience, specialization examined chi square test. The statistically significant with p < 0.01 further logistic regression model. Overall studied parameters very low (2%); only 59.8% received their dose time, 18.5% had selection, 31.8% patients duration. OBGYN department much better regarding timing (P 0.001), however proper best adhered abdominal surgeries (OR = 3.64, P 0.002). Male providers significantly less adherent 0.28, but 0.191, 0.028). Anesthetic technicians showed higher than nurses Lack explains adherence surgical high rate broad spectrum use, long inappropriate .We recommend adopting training all accordingly.