Evaluation of potential protein biomarkers in patients with high sperm DNA damage.

摘要: The laboratory evaluation of male infertility remains an essential area research as 40-60% cases are attributable to male-related factors. Current sperm analysis methods add only partial information on quality and fertility outcomes. specific underlying cause in most is unknown, while a proportion could be caused by molecular factors such the absence or abnormal expression some proteins. objective this study was screen for associations between protein profiles concentration, motility, DNA fragmentation index patients undergoing clinical setting. Based those parameters, semen samples were categorized either normal abnormal. We screened 34 with various parameters compared them 24 control using one dimensional (1-D) gel electrophoresis mass-spectrometry. In study, we anticipated establish no...