Connectin/titin, giant elastic protein of muscle.
作者： Koscak Maruyama
DOI: 10.1096/FASEBJ.11.5.9141500
关键词:
摘要: The structure and function of the giant elastic protein connectin/titin are described on basis recent investigations. 3000 kDa links Z line to myosin filament in striated muscle sarcomeres. NH2-terminal region connectin is involved binding, COOH-terminal bound onto with an overlap between counter-connectin filaments at M line. PEVK I band shown be mainly responsible for passive tension generation. longitudinal continuity myosin-, actin-free sarcomeres explained by linkage freed extending from both sides lines a sarcomere. role myofibrillar differentiation biodiversity connectin-related proteins animal kingdom briefly reviewed.
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