A selective tropism of transfused oval cells for liver
作者： Jian-Zhi Chen
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摘要: AIM: To explore the biological behaviors of hepatic oval cells after transfused into circulation experimental animals. METHODS: Oval from male SD rat were a female which treated by 2-AAF/CCl4 program, through caudal vein. Sex-determining gene sry located on Y chromosome was examined PCR and in situ hybridization technique liver, kidney spleen animals, respectively. RESULTS: The results cell-transplant experiment showed that detectable only liver but not rats, no signals could be detected control animals. It can also morphologically proved some exogenous had migrated parenchyma settled there. CONCLUSION: result means there are animal localization is specific to liver. This indicates "signal molecules" must exist rats 2-AAF/CCl4. These might play an important role differentiation cells.
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