摘要: Abstract Apolipoprotein(a), apo(a), the distinctive glycoprotein constituent of lipoprotein(a), Lp(a), is synthesized in liver, links covalently to apoB100-lipoprotein, and travels so linked plasma tissue sites where removal mechanisms are yet undetermined. Depending on redox status surrounding milieu, apo(a) may re-acquire its unbound state shown have structural functional properties different from those bound form. Apo(a) potentially athero-thrombogenic, a property which be influenced by size, sequence polymorphism, type lipoprotein it inflammatory vessel wall. This set variables must taken into account when assessing cardiovascular pathogenicity free apo(a).
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