Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM‑1

作者: Hao Yang , Mahesh Aitha , Amy R. Marts , Alyssa Hetrick , Brian Bennett

DOI: 10.1021/JA410376S

关键词:

摘要: … In an effort to characterize the roles of each metal ion in metallo-β-lactamase NDM-1, heterodimetallic analogues (CoCo-, ZnCo-, and CoCd-) of the enzyme were generated and …

参考文章(90)
Brian Bennett, EPR of Cobalt-Substituted Zinc Enzymes Metals in Biology. pp. 345- 370 ,(2010) , 10.1007/978-1-4419-1139-1_10
A. Carfi, S. Pares, E. Duée, M. Galleni, C. Duez, J. M. Frère, O. Dideberg, The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. The EMBO Journal. ,vol. 14, pp. 4914- 4921 ,(1995) , 10.1002/J.1460-2075.1995.TB00174.X
Ricardo Luiz Damatto, Marina Politi Okoshi, Katashi Okoshi, Daniele Mendes Guizoni, Aline Regina Ruiz Lima, Luana Urbano Pagan, Paula Felippe Martinez, Marcelo Diarcadia Mariano Cezar, Mariana Janini Gomes, Camila Bonomo, Growth hormone administration alters protein expression in skeletal muscle of rats with aortic stenosis-induced heart failure The FASEB Journal. ,vol. 27, pp. 1- ,(2013)
N.C.J. Strynadka, D.T. King, New Delhi Metallo-Beta-Lactamase: Structural Insights into Beta-Lactam Recognition and Inhibition Journal of the American Chemical Society. ,vol. 134, pp. 11362- 11365 ,(2012) , 10.2210/PDB4EXS/PDB
Sarah M. Drawz, Robert A. Bonomo, Three Decades of β-Lactamase Inhibitors Clinical Microbiology Reviews. ,vol. 23, pp. 160- 201 ,(2010) , 10.1128/CMR.00037-09
Jonathan Crisp, Rebecca Conners, James D. Garrity, Anne L. Carenbauer, Michael W. Crowder, James Spencer, Structural basis for the role of Asp-120 in metallo-beta-lactamases. Biochemistry. ,vol. 46, pp. 10664- 10674 ,(2007) , 10.1021/BI700707U
Javier M González, María-Rocío Meini, Pablo E Tomatis, Francisco J Medrano Martín, Julia A Cricco, Alejandro J Vila, Metallo-β-lactamases withstand low Zn(II) conditions by tuning metal-ligand interactions Nature Chemical Biology. ,vol. 8, pp. 698- 700 ,(2012) , 10.1038/NCHEMBIO.1005
Leticia I. Llarrull, Mariana F. Tioni, Jason Kowalski, Brian Bennett, Alejandro J. Vila, Evidence for a Dinuclear Active Site in the Metallo-β-lactamase BcII with Substoichiometric Co(II) A NEW MODEL FOR METAL UPTAKE Journal of Biological Chemistry. ,vol. 282, pp. 30586- 30595 ,(2007) , 10.1074/JBC.M704613200
Megan J. Hawk, Robert M. Breece, Christine E. Hajdin, Katherine M. Bender, Zhenxin Hu, Alison L. Costello, Brian Bennett, David L. Tierney, Michael W. Crowder, Differential Binding of Co(II) and Zn(II) to Metallo-β-Lactamase Bla2 from Bacillus anthracis Journal of the American Chemical Society. ,vol. 131, pp. 10753- 10762 ,(2009) , 10.1021/JA900296U
Beiwen Zheng, Shuguang Tan, Jia Gao, Huiming Han, Jun Liu, Guangwen Lu, Di Liu, Yong Yi, Baoli Zhu, George F. Gao, An unexpected similarity between antibiotic-resistant NDM-1 and beta-lactamase II from Erythrobacter litoralis Protein & Cell. ,vol. 2, pp. 250- 258 ,(2011) , 10.1007/S13238-011-1027-0