Postoperative adjuvant irradiation: effects on tranverse rectus abdominis muscle flap breast reconstruction.

作者: Nho V. Tran , Gregory R. D. Evans , Stephen S. Kroll , Bonnie J. Baldwin , Michael J. Miller

DOI: 10.1097/00006534-200008000-00011

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摘要: The use of postoperative irradiation following oncologic breast surgery is dictated by tumor pathology, margins, and lymph node involvement. Although negatively influences implant reconstruction, it less clear what effect has on autogenous tissue. This study evaluated the transverse rectus abdominis muscle (TRAM) flap reconstruction. A retrospective review was performed all patients undergoing immediate TRAM reconstruction followed between 1988 1998. Forty-one with a median age 48 years received an average 50.99 Gy fractionated within 6 months after All except two adjuvant chemotherapy. Data were obtained from personal communication, physical examination, chart, photographic review. minimum follow-up time 1 year, 3 years, completion radiation therapy. Nine pedicled flaps 32 microvascular transfer. Fourteen had bilateral but administered unilaterally to higher risk local recurrence. remaining 27 unilateral examined at least year radiotherapy. No loss occurred, 10 (24 percent) required additional correct contracture. (22 maintained normal volume. Hyperpigmentation occurred in 37 percent patients, 56 noted have firm Palpable fat necrosis 34 symmetry 78 percent. Because numbers small, there no statistical difference free group. However, as group, findings statistically significant when compared 1,443 nonirradiated patients. Despite success transfer, unpredictable volume, contour, make difficult achieve consistent results using irradiation. this setting should be approached cautiously, delayed selected considered. Patients aware that multiple revisions and, possibly, are necessary progressive deformity

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