Anatomic and Clinical Pathology
作者： Annarosaria De Chiara , Angelo Paolo Dei Tos
DOI: 10.1007/978-88-470-1869-3_1
关键词:
摘要: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal in GI tract. These derive from Cajal cells or their precursors. The oncogenic drivers tyrosine kinase enzymes (KIT) and, to a lesser degree, platelet- derived growth factor receptor alpha (PDGFRA), both of which become constitutively activated following certain primary mutations. mutations mostly c- KIT gene and rarely PDGFRA.
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sci-hub.st 参考文章(94)
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