Maximizing Pregnancy Rates and Limiting Higher-Order Multiple Conceptions by Determining the Optimal Number of Embryos to Transfer Based on Quality

摘要: Abstract Objective: To define statistical thresholds for the number of embryos to be transferred achieve an optimal pregnancy rate and keep higher-order multiple conceptions (pregnancy with more than two fetal sacs cardiac activity) within acceptable limit. Design: A retrospective review patient records. Setting: Private practice assisted reproductive technology (ART) facility. Patient(s): Seven hundred fifty-four consecutive patients who underwent IVF-ET from 1994–1996. Intervention(s): Embryo grading score system used on day 3 embryo transfer. Main Outcome Measure(s): Implantation, pregnancy, conception rates. Result(s): For women ≤35 years old, transfer up four poor-quality, fair-quality, or good-quality is eliminate any risk pregnancies. Transfer three recommended 36 39 old. In are ≥40 five need regardless quality. Conclusion(s): The mean cumulative can as a reference determine predict outcome.