摘要: Cough persisting beyond 8 weeks (ie, chronic cough) is one of the most common reasons for an outpatient visit. A protracted cough can negatively affect one's quality life by causing anxiety, physical discomfort, social isolation, and personal embarrassment. Herein, anatomy physiology reflex are reviewed. Upper airway syndrome, asthma, eosinophilic bronchitis, gastroesophageal reflux disease account after excluding smoking, angiotensin-converting enzyme inhibitor use, bronchitis. Many patients have more than reason cough. Treating underlying cause(s) resolves in instances. There some coughs that seem refractory despite extensive work-up. The possibility a hypersensitive response has been proposed to explain these cases. Several clinical algorithms evaluate presented.