Research and Global Health Emergencies: On the Essential Role of Best Practice

摘要: This article addresses an important, overlooked regulatory challenge during global health emergencies (GHEs). It provides novel insights into how, and why, best practice can support decision makers in interpreting implementing key guidance on conducting research GHEs. The ability to conduct before, after such events is crucial. recent West-African Ebola outbreaks the Zika virus have highlighted considerable room for improvement meeting imperative rapidly develop effective therapies. A means of effectively capturing these experiences folding them future decision-making lacking; need practical translational measures remains. community lies extracting meaningful action-guiding content from pre-existing guidelines-which draw upon examples guidelines 'in action'-that assist determining how act a particular (future) situation. Insights are provided role as do so; provide invaluable high-level guidance; overarching retain their necessary level generality flexibility, whilst corresponding examples-which incorporate important lessons learned-illustrate be interpreted at level.