Extracranial vasodilatation mediated by vasoactive intestinal polypeptide (VIP)

作者: P.J. Goadsby , G.J. MacDonald

DOI: 10.1016/0006-8993(85)90535-9

关键词:

摘要: Pooled antisera to vasoactive intestinal polypeptide were used block neurogenic extracranial vasodilatation elicited from either brainstem (locus coeruleus) or pterygopalatine ganglion stimulation in the cat. Vasodilatation was not inhibited by sham immune sera, bradykinin substance P. The efferent pathway for locus coeruleus traverses facial nerve (greater superficial petrosal branch) and otic ganglia. Its blockade demonstrates a novel action of peptide transmitter expression central response.

参考文章(24)
L.-I. Larsson, L. Edvinsson, J. Fahrenkrug, R. Håkanson, Ch. Owman, Immunohistochemical localization of a vasodilatory polypeptide (VIP) in cerebrovascular nerves. Brain Research. ,vol. 113, pp. 400- 404 ,(1976) , 10.1016/0006-8993(76)90951-3
K D Bhoola, J Morley, M Schachter, L H Smaje, Vasodilatation in the submaxillary gland of the cat. The Journal of Physiology. ,vol. 179, pp. 172- 184 ,(1965) , 10.1113/JPHYSIOL.1965.SP007656
R. Uddman, L. Malm, F. Sundler, The Origin of Vasoactive Intestinal Polypeptide (VIP) Nerves in the Feline Nasal Mucosa Acta Oto-Laryngologica. ,vol. 89, pp. 152- 156 ,(1980) , 10.3109/00016488009127121
HENRY S. FORBES, CEREBRAL CIRCULATION Archives of Neurology & Psychiatry. ,vol. 37, pp. 776- 781 ,(1937) , 10.1001/ARCHNEURPSYC.1937.02260160076008
J. VAITUKAITIS, J. B. ROBBINS, E. NIESCHLAG, G. T. ROSS, A METHOD FOR PRODUCING SPECIFIC ANTISERA WITH SMALL DOSES OF IMMUNOGEN The Journal of Clinical Endocrinology and Metabolism. ,vol. 33, pp. 988- 991 ,(1971) , 10.1210/JCEM-33-6-988
G.L. Ruskell, Facial parasympathetic innervation of the choroidal blood vessels in monkeys. Experimental Eye Research. ,vol. 12, pp. 166- 172 ,(1971) , 10.1016/0014-4835(71)90085-6
P.J. Goadsby, G.A. Lambert, J.W. Lance, Effects of locus coeruleus stimulation on carotid vascular resistance in the cat Brain Research. ,vol. 278, pp. 175- 183 ,(1983) , 10.1016/0006-8993(83)90236-6